| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| argH | ydaO | Lgor_1530 | Lgor_1945 | Argininosuccinate lyase. | C32 tRNA thiolase; Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32). The sulfur atoms are provided by the cysteine/cysteine desulfurase (IscS) system. | 0.543 |
| guaA | moeZ_1 | Lgor_1544 | Lgor_1269 | GMP synthetase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | Thiazole biosynthesis adenylyltransferase ThiF. | 0.519 |
| guaA | pgi | Lgor_1544 | Lgor_1233 | GMP synthetase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | Glucose-6-phosphate isomerase; Belongs to the GPI family. | 0.511 |
| guaA | pth | Lgor_1544 | Lgor_0012 | GMP synthetase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | peptidyl-tRNA hydrolase; The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis. Belongs to the PTH family. | 0.540 |
| guaA | ydaO | Lgor_1544 | Lgor_1945 | GMP synthetase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | C32 tRNA thiolase; Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32). The sulfur atoms are provided by the cysteine/cysteine desulfurase (IscS) system. | 0.799 |
| mfd | pth | Lgor_1797 | Lgor_0012 | Transcription-repair coupling factor; Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site; In the C-terminal section; belongs to the helicase family. RecG subfamily. | peptidyl-tRNA hydrolase; The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis. Belongs to the PTH family. | 0.709 |
| mfd | ydaO | Lgor_1797 | Lgor_1945 | Transcription-repair coupling factor; Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site; In the C-terminal section; belongs to the helicase family. RecG subfamily. | C32 tRNA thiolase; Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32). The sulfur atoms are provided by the cysteine/cysteine desulfurase (IscS) system. | 0.547 |
| moeZ_1 | guaA | Lgor_1269 | Lgor_1544 | Thiazole biosynthesis adenylyltransferase ThiF. | GMP synthetase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | 0.519 |
| moeZ_1 | thiS | Lgor_1269 | Lgor_1266 | Thiazole biosynthesis adenylyltransferase ThiF. | Thiamine biosynthesis protein ThiS. | 0.995 |
| moeZ_1 | ydaO | Lgor_1269 | Lgor_1945 | Thiazole biosynthesis adenylyltransferase ThiF. | C32 tRNA thiolase; Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32). The sulfur atoms are provided by the cysteine/cysteine desulfurase (IscS) system. | 0.613 |
| pcm | tolC | Lgor_1943 | Lgor_1944 | protein-L-isoaspartate-O-methyltransferase. | Outer membrane protein TolC. | 0.783 |
| pcm | ydaO | Lgor_1943 | Lgor_1945 | protein-L-isoaspartate-O-methyltransferase. | C32 tRNA thiolase; Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32). The sulfur atoms are provided by the cysteine/cysteine desulfurase (IscS) system. | 0.733 |
| pgi | guaA | Lgor_1233 | Lgor_1544 | Glucose-6-phosphate isomerase; Belongs to the GPI family. | GMP synthetase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | 0.511 |
| pgi | wecB_3 | Lgor_1233 | Lgor_0972 | Glucose-6-phosphate isomerase; Belongs to the GPI family. | UDP-N-acetylglucosamine 2-epimerase; Belongs to the UDP-N-acetylglucosamine 2-epimerase family. | 0.486 |
| pgi | ydaO | Lgor_1233 | Lgor_1945 | Glucose-6-phosphate isomerase; Belongs to the GPI family. | C32 tRNA thiolase; Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32). The sulfur atoms are provided by the cysteine/cysteine desulfurase (IscS) system. | 0.555 |
| pth | guaA | Lgor_0012 | Lgor_1544 | peptidyl-tRNA hydrolase; The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis. Belongs to the PTH family. | GMP synthetase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | 0.540 |
| pth | mfd | Lgor_0012 | Lgor_1797 | peptidyl-tRNA hydrolase; The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis. Belongs to the PTH family. | Transcription-repair coupling factor; Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site; In the C-terminal section; belongs to the helicase family. RecG subfamily. | 0.709 |
| pth | ydaO | Lgor_0012 | Lgor_1945 | peptidyl-tRNA hydrolase; The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis. Belongs to the PTH family. | C32 tRNA thiolase; Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32). The sulfur atoms are provided by the cysteine/cysteine desulfurase (IscS) system. | 0.583 |
| thiS | moeZ_1 | Lgor_1266 | Lgor_1269 | Thiamine biosynthesis protein ThiS. | Thiazole biosynthesis adenylyltransferase ThiF. | 0.995 |
| thiS | ydaO | Lgor_1266 | Lgor_1945 | Thiamine biosynthesis protein ThiS. | C32 tRNA thiolase; Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32). The sulfur atoms are provided by the cysteine/cysteine desulfurase (IscS) system. | 0.859 |