STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
hoxHCoenzyme F420-reducing hydrogenase, alpha subunit. (430 aa)    
Predicted Functional Partners:
hoxY
Sulfhydrogenase subunit delta.
 
 0.998
Lgor_2155
Hydrogenase subunit.
 
   
 0.975
vhtD
Hydrogenase expression/formation protein.
 
  
 0.974
hydG
Hydrogenase/sulfur reductase gamma subunit.
 
   
 0.970
hypF
Hydrogenase maturation protein HypF; Involved in the maturation of [NiFe] hydrogenases. Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of [NiFe]-hydrogenases. HypF functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide.
 
   
 0.694
hypE
Hydrogenase expression/formation protein HypE.
 
   
 0.670
hypD
Hydrogenase expression/formation protein HypD; Belongs to the HypD family.
 
   
 0.664
sdhB
Succinate dehydrogenase iron-sulfur subunit.
    
 0.588
hypC
Hydrogenase expression/formation protein HypC.
 
   
 0.565
fixL_2
Two-component sensor histidine kinase.
     
  0.561
Your Current Organism:
Fluoribacter gormanii
NCBI taxonomy Id: 464
Other names: ATCC 33297, ATCC 33342, CCUG 12267, CIP 104724, DSM 16641, DSM 25296, F. gormanii, Legionella gormanii, NCTC 11401, strain LS-13
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