Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
ptpA_1Prolyl oligopeptidase. (658 aa)    
Predicted Functional Partners:
ptpA
Prolyl tripeptidyl peptidase precursor.
  
     0.723
ampC_2
Beta-lactamase.
 
     0.622
per1
Beta-lactamase.
  
     0.577
blaFEZ-1
Metallo-beta-lactamase L1 precursor.
  
     0.556
guaA
GMP synthetase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP.
     
  0.543
zraS_1
Signal transduction histidine kinase.
       0.494
cyaB_1
Guanylate cyclase.
       0.494
Lgor_2884
GNAT family acetyltransferase.
  
    0.437
cpg2_1
Carboxypeptidase G2.
  
     0.413
add_4
Adenosine deaminase.
  
  
  0.401
Your Current Organism:
Fluoribacter gormanii
NCBI taxonomy Id: 464
Other names: ATCC 33297, ATCC 33342, CCUG 12267, CIP 104724, DSM 16641, DSM 25296, F. gormanii, Legionella gormanii, NCTC 11401, strain LS-13
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