Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
pbpCPenicillin binding protein 1C. (768 aa)    
Predicted Functional Partners:
Lgor_2428
Hypothetical protein; Alpha-2-macroglobulin family N-terminal region.
   
 0.981
mrdA
Penicillin-binding protein 2; Catalyzes cross-linking of the peptidoglycan cell wall. Belongs to the transpeptidase family. MrdA subfamily.
  
  
 0.912
mrcA
Putative peptidoglycan synthetase, penicillin-binding protein 1A.
  
  
0.897
ftsI
Transpeptidase involved in septal peptidoglycan synthesis (penicillin-binding protein 3); Catalyzes cross-linking of the peptidoglycan cell wall at the division septum; Belongs to the transpeptidase family. FtsI subfamily.
     
 0.894
dacB_2
D-alanyl-D-alanine carboxypeptidase/D-alanyl-D-alanine-endopeptidase.
   
 
 0.870
dacB_1
D-Ala-D-Ala carboxypeptidase.
   
 
 0.870
dacA
D-alanyl-D-alanine carboxypeptidase (penicillin-binding protein 5); Belongs to the peptidase S11 family.
     
 0.866
ampC_2
Beta-lactamase.
     
  0.539
Lgor_1063
D-alanyl-D-alanine carboxypeptidase.
     
  0.539
pbpX
Putative penicillin-binding protein PbpX.
     
  0.539
Your Current Organism:
Fluoribacter gormanii
NCBI taxonomy Id: 464
Other names: ATCC 33297, ATCC 33342, CCUG 12267, CIP 104724, DSM 16641, DSM 25296, F. gormanii, Legionella gormanii, NCTC 11401, strain LS-13
Server load: low (10%) [HD]