Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
cpxA_2Sensor histidine kinase. (534 aa)    
Predicted Functional Partners:
arcB_1
Sensory box histidine kinase/response regulator.
 
 
 0.964
arcB_4
Sensory histidine-kinase / response regulator.
 
 
 0.963
letS_1
Legionella transmission sensor LetS.
 
0.908
letS_2
Legionella transmission sensor LetS.
 
 
0.888
cyaB_3
Guanylate/adenylate cyclase.
 
 0.849
ompR_2
DNA-binding response regulator in two-component regulatory system with EnvZ.
 
 0.843
cpxR
Transcriptional regulatory protein CpxR.
  
 0.838
cph2_3
Sensory box (GGDEF/EAL domain) regulatory protein.
   
 0.824
ompR_1
DNA-binding response regulator in two-component regulatory system with EnvZ.
  
 0.819
ompR_3
DNA-binding response regulator in two-component regulatory system with EnvZ.
 
 0.802
Your Current Organism:
Fluoribacter gormanii
NCBI taxonomy Id: 464
Other names: ATCC 33297, ATCC 33342, CCUG 12267, CIP 104724, DSM 16641, DSM 25296, F. gormanii, Legionella gormanii, NCTC 11401, strain LS-13
Server load: low (20%) [HD]