Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
glpKGlycerol kinase; Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate. (488 aa)    
Predicted Functional Partners:
glpD
Glycerol-3-phosphate dehydrogenase; Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.
 0.999
plsY
Transmembrane protein; Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.
     
 0.890
adhC2
Zinc-type alcohol dehydrogenase-like protein.
     
 0.863
ugpQ
Glycerophosphodiester phosphodiesterase, cytosolic.
 
 
 0.833
gpsA
Glycerol-3-phosphate dehydrogenase (NAD+); Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
   
 0.780
Lgor_3003
Glycerophosphoryl diester phosphodiesterase.
 
 
 0.711
succ
succinyl-CoA synthetase subunit beta; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
    
 
 0.656
lysAC_1
Diaminopimelate decarboxylase, aspartate kinase (fusion of lysA and lysC).
    
 0.647
lysAC_2
Diaminopimelate decarboxylase, aspartate kinase (fusion of lysA and lysC); Belongs to the Orn/Lys/Arg decarboxylase class-II family.
    
 0.647
bcp
Acetylpolyamine aminohydrolase.
   
   0.643
Your Current Organism:
Fluoribacter gormanii
NCBI taxonomy Id: 464
Other names: ATCC 33297, ATCC 33342, CCUG 12267, CIP 104724, DSM 16641, DSM 25296, F. gormanii, Legionella gormanii, NCTC 11401, strain LS-13
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