node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
dksA | pieE | Lgor_1672 | Lgor_2741 | DnaK suppressor protein; Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters. Also required for regulation of fis expression. | Substrate of the Dot/Icm secretion system. | 0.723 |
enhA_3 | pieE | Lgor_2740 | Lgor_2741 | Enhanced entry protein EnhA. | Substrate of the Dot/Icm secretion system. | 0.529 |
hisIE | map_1 | Lgor_2857 | Lgor_1549 | Histidine biosynthesis bifunctional protein HisIE; In the N-terminal section; belongs to the PRA-CH family. | Methionine aminopeptidase; Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed; Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily. | 0.870 |
hisIE | map_1-2 | Lgor_2857 | Lgor_2372 | Histidine biosynthesis bifunctional protein HisIE; In the N-terminal section; belongs to the PRA-CH family. | Methionine aminopeptidase; Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed; Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily. | 0.870 |
hisIE | pieE | Lgor_2857 | Lgor_2741 | Histidine biosynthesis bifunctional protein HisIE; In the N-terminal section; belongs to the PRA-CH family. | Substrate of the Dot/Icm secretion system. | 0.507 |
hisIE | rpmE | Lgor_2857 | Lgor_0614 | Histidine biosynthesis bifunctional protein HisIE; In the N-terminal section; belongs to the PRA-CH family. | 50S ribosomal protein L31; Binds the 23S rRNA. | 0.916 |
map_1 | hisIE | Lgor_1549 | Lgor_2857 | Methionine aminopeptidase; Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed; Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily. | Histidine biosynthesis bifunctional protein HisIE; In the N-terminal section; belongs to the PRA-CH family. | 0.870 |
map_1 | pieE | Lgor_1549 | Lgor_2741 | Methionine aminopeptidase; Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed; Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily. | Substrate of the Dot/Icm secretion system. | 0.713 |
map_1 | rpsN | Lgor_1549 | Lgor_0256 | Methionine aminopeptidase; Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed; Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily. | 30S ribosomal protein S14; Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site; Belongs to the universal ribosomal protein uS14 family. | 0.968 |
map_1-2 | hisIE | Lgor_2372 | Lgor_2857 | Methionine aminopeptidase; Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed; Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily. | Histidine biosynthesis bifunctional protein HisIE; In the N-terminal section; belongs to the PRA-CH family. | 0.870 |
map_1-2 | pieE | Lgor_2372 | Lgor_2741 | Methionine aminopeptidase; Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed; Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily. | Substrate of the Dot/Icm secretion system. | 0.713 |
map_1-2 | rpsN | Lgor_2372 | Lgor_0256 | Methionine aminopeptidase; Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed; Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily. | 30S ribosomal protein S14; Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site; Belongs to the universal ribosomal protein uS14 family. | 0.968 |
pieE | dksA | Lgor_2741 | Lgor_1672 | Substrate of the Dot/Icm secretion system. | DnaK suppressor protein; Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters. Also required for regulation of fis expression. | 0.723 |
pieE | enhA_3 | Lgor_2741 | Lgor_2740 | Substrate of the Dot/Icm secretion system. | Enhanced entry protein EnhA. | 0.529 |
pieE | hisIE | Lgor_2741 | Lgor_2857 | Substrate of the Dot/Icm secretion system. | Histidine biosynthesis bifunctional protein HisIE; In the N-terminal section; belongs to the PRA-CH family. | 0.507 |
pieE | map_1 | Lgor_2741 | Lgor_1549 | Substrate of the Dot/Icm secretion system. | Methionine aminopeptidase; Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed; Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily. | 0.713 |
pieE | map_1-2 | Lgor_2741 | Lgor_2372 | Substrate of the Dot/Icm secretion system. | Methionine aminopeptidase; Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed; Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily. | 0.713 |
pieE | rpmB | Lgor_2741 | Lgor_0048 | Substrate of the Dot/Icm secretion system. | 50S ribosomal protein L28; Belongs to the bacterial ribosomal protein bL28 family. | 0.697 |
pieE | rpmE | Lgor_2741 | Lgor_0614 | Substrate of the Dot/Icm secretion system. | 50S ribosomal protein L31; Binds the 23S rRNA. | 0.406 |
pieE | rpmG | Lgor_2741 | Lgor_0049 | Substrate of the Dot/Icm secretion system. | 50S ribosomal protein L33; Belongs to the bacterial ribosomal protein bL33 family. | 0.533 |