STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
guaDGuanine deaminase; Catalyzes the hydrolytic deamination of guanine, producing xanthine and ammonia; Belongs to the metallo-dependent hydrolases superfamily. ATZ/TRZ family. (436 aa)    
Predicted Functional Partners:
hpt
Hypoxanthine phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family.
 
  
 0.828
punA
Purine nucleoside phosphorylase 1; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.
    
 0.807
CUO46548.1
Inosine-uridine preferring nucleoside hydrolase.
    
 0.801
xpt
Xanthine phosphoribosyltransferase; Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis.
     
 0.798
fieF
Ferrous-iron efflux pump FieF; Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family.
       0.773
xanP
Xanthine permease XanP.
    0.761
gcvP
Glycine dehydrogenase [decarboxylating]; Belongs to the GcvP family.
 
 
 0.746
rnfB
Nitrogen fixation protein rnfB; Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane. Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfB subfamily.
    
  0.733
upp
Uracil phosphoribosyltransferase.
  
 
 0.484
rocF
Arginase; Belongs to the arginase family.
 
  
 0.463
Your Current Organism:
Parabacteroides merdae
NCBI taxonomy Id: 46503
Other names: ATCC 43184, Bacteroides merdae, CCUG 38734, CIP 104202, JCM 9497, NCTC 13052, P. merdae, VPI T4-1
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