node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
cmk | guaA | AA415_00972 | AA415_02618 | Cytidylate kinase. | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | 0.413 |
cmk | guaB | AA415_00972 | AA415_01818 | Cytidylate kinase. | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 0.512 |
cmk | pyrH | AA415_00972 | AA415_00738 | Cytidylate kinase. | Uridylate kinase; Catalyzes the reversible phosphorylation of UMP to UDP. | 0.518 |
cmk | surE | AA415_00972 | AA415_00793 | Cytidylate kinase. | Putative 5'-nucleotidase, SurE-like; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family. | 0.900 |
cmk | thrZ | AA415_00972 | AA415_01441 | Cytidylate kinase. | threonine--tRNA ligase 2. | 0.915 |
gmk_2 | guaA | AA415_02830 | AA415_02618 | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | 0.968 |
gmk_2 | guaB | AA415_02830 | AA415_01818 | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 0.589 |
gmk_2 | pyrH | AA415_02830 | AA415_00738 | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | Uridylate kinase; Catalyzes the reversible phosphorylation of UMP to UDP. | 0.737 |
gmk_2 | surE | AA415_02830 | AA415_00793 | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | Putative 5'-nucleotidase, SurE-like; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family. | 0.909 |
gmk_2 | thrZ | AA415_02830 | AA415_01441 | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | threonine--tRNA ligase 2. | 0.609 |
guaA | cmk | AA415_02618 | AA415_00972 | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | Cytidylate kinase. | 0.413 |
guaA | gmk_2 | AA415_02618 | AA415_02830 | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | 0.968 |
guaA | guaB | AA415_02618 | AA415_01818 | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 0.999 |
guaA | purA | AA415_02618 | AA415_01571 | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. | 0.934 |
guaA | purB | AA415_02618 | AA415_01832 | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | Adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | 0.890 |
guaA | purH | AA415_02618 | AA415_03064 | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | Putative bifunctional purine biosynthesis protein, PurH-like. | 0.910 |
guaA | pyrF | AA415_02618 | AA415_01958 | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | Orotidine 5'-phosphate decarboxylase; Belongs to the OMP decarboxylase family. Type 2 subfamily. | 0.638 |
guaA | pyrH | AA415_02618 | AA415_00738 | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | Uridylate kinase; Catalyzes the reversible phosphorylation of UMP to UDP. | 0.777 |
guaA | surE | AA415_02618 | AA415_00793 | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | Putative 5'-nucleotidase, SurE-like; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family. | 0.944 |
guaB | cmk | AA415_01818 | AA415_00972 | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | Cytidylate kinase. | 0.512 |