Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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experimentally determined
co-expression
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gene co-occurrence
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[Homology]
Score
cobKprecorrin-6A reductase; Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A. (631 aa)    
Predicted Functional Partners:
cbiH
cobalt-precorrin-3B C(17)-methyltransferase.
 
  
 0.999
cobL
precorrin-6Y C(5,15)-methyltransferase (decarboxylating).
 
 
 0.999
cbiF
Cobalt-precorrin-4 C(11)-methyltransferase.
 
  
 0.999
cobI
Precorrin-2 C(20)-methyltransferase; Methylates cobalt-precorrin-2 at the C-20 position to produce cobalt-precorrin-3A in the anaerobic cobalamin biosynthesis pathway.
 
 
 0.998
cobQ
Cobyric acid synthase; Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. Belongs to the CobB/CobQ family. CobQ subfamily.
 
  
 0.998
cbiK
Sirohydrochlorin cobaltochelatase.
 
  
 0.991
cbiKp
CbiKP-like sirohydrochlorin cobaltochelatase precursor.
 
  
 0.983
cobS
Cobalamin synthase; Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'- phosphate; Belongs to the CobS family.
 
  
 0.974
cobB_2
Cobyrinic acid A,C-diamide synthase.
 
  
 0.955
cobD-2
Cobalamin biosynthesis protein; Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group.
 
  
 0.946
Your Current Organism:
Bacteroides stercoris
NCBI taxonomy Id: 46506
Other names: ATCC 43183, B. stercoris, CCUG 38733, CIP 104203, JCM 9496, NCTC 13053, VPI B5-21
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