STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
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[Homology]
Score
ACS29911.1Putative glutamate--cysteine ligase/putative amino acid ligase; PFAM: Endonuclease/Exonuclease/phosphatase family; TIGRFAM: glutamate--cysteine ligase/gamma-glutamylcysteine synthetase, Streptococcus agalactiae type. (902 aa)    
Predicted Functional Partners:
ACS29912.1
5'-nucleotidase/2',3'-cyclic phosphodiesterase-like hydrolase; PFAM: Calcineurin-like phosphoesterase; 5'-nucleotidase, C-terminal domain; Belongs to the 5'-nucleotidase family.
  
 0.998
ACS30568.1
Uridine kinase.
 
  
  0.914
ACS29773.1
PFAM: Thymidine kinase.
  
  
  0.911
ACS30034.1
PFAM: Cytidine and deoxycytidylate deaminase zinc-binding region; TIGRFAM: cytidine deaminase, homotetrameric.
    
  0.905
ACS30035.1
PFAM: Pyrimidine nucleoside phosphorylase C-terminal domain; Glycosyl transferase family, helical bundle domain; Glycosyl transferase family, a/b domain; TIGRFAM: pyrimidine-nucleoside phosphorylase.
    
  0.905
purH
PFAM: AICARFT/IMPCHase bienzyme; MGS-like domain; TIGRFAM: phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase.
    
  0.904
gmk
Guanylate kinase; Essential for recycling GMP and indirectly, cGMP.
    
  0.903
guaA
GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP.
    
  0.903
upp
Uracil phosphoribosyltransferase; Catalyzes the conversion of uracil and 5-phospho-alpha-D- ribose 1-diphosphate (PRPP) to UMP and diphosphate.
    
  0.902
ACS29871.1
GMP synthase family protein.
    
  0.901
Your Current Organism:
Micrococcus luteus NCTC 2665
NCBI taxonomy Id: 465515
Other names: M. luteus NCTC 2665, Micrococcus luteus ATCC 4698, Micrococcus luteus CCM 169, Micrococcus luteus DSM 20030, Micrococcus luteus Fleming 2665, Micrococcus luteus NCIB 9278, Micrococcus luteus str. NCTC 2665, Micrococcus luteus strain NCTC 2665
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