STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ACS30315.1Sodium/ prolin symporter; Catalyzes the sodium-dependent uptake of extracellular L- proline; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family. (544 aa)    
Predicted Functional Partners:
ACS31424.1
PFAM: Aldehyde dehydrogenase family; Proline dehydrogenase; Belongs to the aldehyde dehydrogenase family.
 
  
 0.961
apt
Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
   
  
 0.668
ACS31309.1
SNF family Na+-dependent transporter; PFAM: Sodium:neurotransmitter symporter family; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.
 
  
 0.564
ACS30387.1
PFAM: Carbon starvation protein CstA.
  
    0.557
ACS30314.1
ATP-dependent helicase HrpA; PFAM: Domain of unknown function (DUF1605); Helicase conserved C-terminal domain; Helicase associated domain (HA2); TIGRFAM: ATP-dependent helicase HrpA.
       0.542
lexA
SOS-response transcriptional repressor, LexA; Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.
   
  
 0.530
ACS30727.1
PFAM: Cytochrome C oxidase subunit II, periplasmic domain; TIGRFAM: cytochrome c oxidase, subunit II.
   
  
 0.429
ACS31034.1
ABC-type polar amino acid transport system, ATPase component; PFAM: ABC transporter.
  
  
 0.423
ACS31355.1
ABC-type polar amino acid transport system, ATPase component; PFAM: ABC transporter.
  
  
 0.423
Your Current Organism:
Micrococcus luteus NCTC 2665
NCBI taxonomy Id: 465515
Other names: M. luteus NCTC 2665, Micrococcus luteus ATCC 4698, Micrococcus luteus CCM 169, Micrococcus luteus DSM 20030, Micrococcus luteus Fleming 2665, Micrococcus luteus NCIB 9278, Micrococcus luteus str. NCTC 2665, Micrococcus luteus strain NCTC 2665
Server load: low (20%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.