STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ACS30359.1Nicotinamidase-like amidase; PFAM: Isochorismatase family. (227 aa)    
Predicted Functional Partners:
ACS30360.1
Putative nicotinate phosphoribosyltransferase; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Belongs to the NAPRTase family.
 
 0.999
cobB
NAD-dependent protein deacetylase, SIR2 family; PFAM: Sir2 family; Belongs to the sirtuin family. Class III subfamily.
  
 0.916
ACS30199.1
PFAM: Inosine-uridine preferring nucleoside hydrolase.
     
 0.907
ACS30099.1
Purine nucleotide phosphorylase; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.
    
 0.905
rpsL
SSU ribosomal protein S12P; With S4 and S5 plays an important role in translational accuracy.
  
  
 0.780
rpoB
DNA-directed RNA polymerase, beta subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
      
 0.756
gyrB
DNA gyrase subunit B; A type II topoisomerase that negatively supercoils DNA in an ATP-dependent manner. About 140 bp of DNA wraps around gyrase in the presence or absence of ATP, when ATP is added negative supercoils are made.
      
 0.755
clpS
Uncharacterized conserved protein; Involved in the modulation of the specificity of the ClpAP- mediated ATP-dependent protein degradation; Belongs to the ClpS family.
       0.651
ACS30362.1
Hypothetical protein; PFAM: Domain of unknown function (DUF2017).
       0.648
murI
Glutamate racemase; Provides the (R)-glutamate required for cell wall biosynthesis.
       0.646
Your Current Organism:
Micrococcus luteus NCTC 2665
NCBI taxonomy Id: 465515
Other names: M. luteus NCTC 2665, Micrococcus luteus ATCC 4698, Micrococcus luteus CCM 169, Micrococcus luteus DSM 20030, Micrococcus luteus Fleming 2665, Micrococcus luteus NCIB 9278, Micrococcus luteus str. NCTC 2665, Micrococcus luteus strain NCTC 2665
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