STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ACS30498.1PFAM: Ribose/Galactose Isomerase; TIGRFAM: sugar-phosphate isomerases, RpiB/LacA/LacB family; ribose 5-phosphate isomerase. (157 aa)    
Predicted Functional Partners:
ACS30590.1
Ribulose-5-phosphate 3-epimerase; PFAM: Ribulose-phosphate 3 epimerase family; TIGRFAM: ribulose-phosphate 3-epimerase; Belongs to the ribulose-phosphate 3-epimerase family.
 
 
 0.948
ACS30649.1
PFAM: Transketolase, thiamine diphosphate binding domain; Transketolase, C-terminal domain; Transketolase, pyrimidine binding domain; TIGRFAM: transketolase, bacterial and yeast; Belongs to the transketolase family.
  
 
 0.932
prs
Ribose-phosphate pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
    
 0.923
ACS30463.1
6-phosphogluconate dehydrogenase (decarboxylating); Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH.
    
 0.917
glyA
Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
 
    0.909
ACS29671.1
Phosphoglucomutase, alpha-D-glucose phosphate-specific; PFAM: Phosphoglucomutase/phosphomannomutase, C-terminal domain; Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III; Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II; Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I; TIGRFAM: phosphoglucomutase, alpha-D-glucose phosphate-specific.
     
  0.900
ACS30647.1
PFAM: Phosphoglucose isomerase; Belongs to the GPI family.
    
 0.873
pdxS
Pyridoxal phosphate synthase yaaD subunit; Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5- phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively. Belongs to the PdxS/SNZ family.
   
 
  0.801
pdxT
Pyridoxal phosphate synthase yaaE subunit; Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS.
     
  0.800
upp
Uracil phosphoribosyltransferase; Catalyzes the conversion of uracil and 5-phospho-alpha-D- ribose 1-diphosphate (PRPP) to UMP and diphosphate.
 
  
 0.786
Your Current Organism:
Micrococcus luteus NCTC 2665
NCBI taxonomy Id: 465515
Other names: M. luteus NCTC 2665, Micrococcus luteus ATCC 4698, Micrococcus luteus CCM 169, Micrococcus luteus DSM 20030, Micrococcus luteus Fleming 2665, Micrococcus luteus NCIB 9278, Micrococcus luteus str. NCTC 2665, Micrococcus luteus strain NCTC 2665
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