STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
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Textmining
[Homology]
Score
ACS30789.1(p)ppGpp synthetase, RelA/SpoT family; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. (759 aa)    
Predicted Functional Partners:
ACS31688.1
Uncharacterized conserved protein; PFAM: Region found in RelA / SpoT proteins.
    
0.938
ACS30041.1
Exopolyphosphatase; PFAM: Protein of unknown function (DUF501); Ppx/GppA phosphatase family.
 
 
 0.929
ACS30038.1
Protein with tetrapyrrole methyltransferase and pyrophosphatase domains; PFAM: MazG nucleotide pyrophosphohydrolase domain.
  
 
 0.921
gmk
Guanylate kinase; Essential for recycling GMP and indirectly, cGMP.
  
 
 0.921
ACS31290.1
PFAM: Ppx/GppA phosphatase family.
  
 
 0.917
ACS30523.1
PFAM: Nucleoside diphosphate kinase; Belongs to the NDK family.
    
 0.913
ACS30609.1
PFAM: Pyruvate kinase, alpha/beta domain; Pyruvate kinase, barrel domain; TIGRFAM: pyruvate kinase; Belongs to the pyruvate kinase family.
   
 
 0.906
ACS31023.1
PFAM: Pyruvate kinase, barrel domain.
   
 
 0.906
ACS30129.1
PFAM: Adenylate and Guanylate cyclase catalytic domain.
     
 0.902
ACS30561.1
Ribonucleoside-diphosphate reductase class Ib alpha subunit; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.
     
 0.902
Your Current Organism:
Micrococcus luteus NCTC 2665
NCBI taxonomy Id: 465515
Other names: M. luteus NCTC 2665, Micrococcus luteus ATCC 4698, Micrococcus luteus CCM 169, Micrococcus luteus DSM 20030, Micrococcus luteus Fleming 2665, Micrococcus luteus NCIB 9278, Micrococcus luteus str. NCTC 2665, Micrococcus luteus strain NCTC 2665
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