node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
AKL66322.1 | AKL68241.1 | M444_13970 | M444_25625 | Hypothetical protein; Belongs to the UPF0301 (AlgH) family. | Vitamin B12-dependent ribonucleotide reductase; Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen. | 0.990 |
AKL67178.1 | AKL67185.1 | M444_19275 | M444_19330 | Kinase. | Nucleoside diphosphate kinase; Catalyzes the formation of nucleoside triphosphate from ATP and nucleoside diphosphate; Belongs to the NDK family. | 0.919 |
AKL67178.1 | AKL67793.1 | M444_19275 | M444_22940 | Kinase. | Ribonucleoside-diphosphate reductase; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides; Belongs to the ribonucleoside diphosphate reductase small chain family. | 0.926 |
AKL67178.1 | AKL68241.1 | M444_19275 | M444_25625 | Kinase. | Vitamin B12-dependent ribonucleotide reductase; Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen. | 0.944 |
AKL67178.1 | adk | M444_19275 | M444_20805 | Kinase. | Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. | 0.424 |
AKL67178.1 | gmk | M444_19275 | M444_07725 | Kinase. | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | 0.559 |
AKL67178.1 | ndk | M444_19275 | M444_12760 | Kinase. | Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. | 0.919 |
AKL67185.1 | AKL67178.1 | M444_19330 | M444_19275 | Nucleoside diphosphate kinase; Catalyzes the formation of nucleoside triphosphate from ATP and nucleoside diphosphate; Belongs to the NDK family. | Kinase. | 0.919 |
AKL67185.1 | AKL67793.1 | M444_19330 | M444_22940 | Nucleoside diphosphate kinase; Catalyzes the formation of nucleoside triphosphate from ATP and nucleoside diphosphate; Belongs to the NDK family. | Ribonucleoside-diphosphate reductase; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides; Belongs to the ribonucleoside diphosphate reductase small chain family. | 0.910 |
AKL67185.1 | AKL68241.1 | M444_19330 | M444_25625 | Nucleoside diphosphate kinase; Catalyzes the formation of nucleoside triphosphate from ATP and nucleoside diphosphate; Belongs to the NDK family. | Vitamin B12-dependent ribonucleotide reductase; Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen. | 0.908 |
AKL67185.1 | adk | M444_19330 | M444_20805 | Nucleoside diphosphate kinase; Catalyzes the formation of nucleoside triphosphate from ATP and nucleoside diphosphate; Belongs to the NDK family. | Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. | 0.927 |
AKL67185.1 | cmk | M444_19330 | M444_09130 | Nucleoside diphosphate kinase; Catalyzes the formation of nucleoside triphosphate from ATP and nucleoside diphosphate; Belongs to the NDK family. | Cytidylate kinase. | 0.924 |
AKL67185.1 | gmk | M444_19330 | M444_07725 | Nucleoside diphosphate kinase; Catalyzes the formation of nucleoside triphosphate from ATP and nucleoside diphosphate; Belongs to the NDK family. | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | 0.928 |
AKL67185.1 | ndk | M444_19330 | M444_12760 | Nucleoside diphosphate kinase; Catalyzes the formation of nucleoside triphosphate from ATP and nucleoside diphosphate; Belongs to the NDK family. | Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. | 0.912 |
AKL67793.1 | AKL67178.1 | M444_22940 | M444_19275 | Ribonucleoside-diphosphate reductase; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides; Belongs to the ribonucleoside diphosphate reductase small chain family. | Kinase. | 0.926 |
AKL67793.1 | AKL67185.1 | M444_22940 | M444_19330 | Ribonucleoside-diphosphate reductase; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides; Belongs to the ribonucleoside diphosphate reductase small chain family. | Nucleoside diphosphate kinase; Catalyzes the formation of nucleoside triphosphate from ATP and nucleoside diphosphate; Belongs to the NDK family. | 0.910 |
AKL67793.1 | AKL68241.1 | M444_22940 | M444_25625 | Ribonucleoside-diphosphate reductase; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides; Belongs to the ribonucleoside diphosphate reductase small chain family. | Vitamin B12-dependent ribonucleotide reductase; Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen. | 0.999 |
AKL67793.1 | adk | M444_22940 | M444_20805 | Ribonucleoside-diphosphate reductase; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides; Belongs to the ribonucleoside diphosphate reductase small chain family. | Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. | 0.923 |
AKL67793.1 | cmk | M444_22940 | M444_09130 | Ribonucleoside-diphosphate reductase; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides; Belongs to the ribonucleoside diphosphate reductase small chain family. | Cytidylate kinase. | 0.922 |
AKL67793.1 | gmk | M444_22940 | M444_07725 | Ribonucleoside-diphosphate reductase; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides; Belongs to the ribonucleoside diphosphate reductase small chain family. | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | 0.911 |