node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
AMN46112.1 | AMN46115.1 | ACG33_03100 | ACG33_03115 | Transketolase; Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate. | Pyruvate kinase; Catalyzes the formation of phosphoenolpyruvate from pyruvate; Belongs to the pyruvate kinase family. | 0.979 |
AMN46112.1 | AMN47646.1 | ACG33_03100 | ACG33_11150 | Transketolase; Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate. | Malate dehydrogenase. | 0.496 |
AMN46112.1 | eno | ACG33_03100 | ACG33_09515 | Transketolase; Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate. | Enolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis. | 0.955 |
AMN46112.1 | gapA | ACG33_03100 | ACG33_03105 | Transketolase; Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate. | Glyceraldehyde-3-phosphate dehydrogenase; Required for glycolysis; catalyzes the formation of 3-phospho-D-glyceroyl phosphate from D-glyceraldehyde 3-phosphate; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. | 0.986 |
AMN46112.1 | gpmA | ACG33_03100 | ACG33_02445 | Transketolase; Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate. | Phosphoglyceromutase; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate; Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily. | 0.867 |
AMN46112.1 | pfp | ACG33_03100 | ACG33_03025 | Transketolase; Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate. | 6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP- PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions. | 0.946 |
AMN46112.1 | pgi | ACG33_03100 | ACG33_04735 | Transketolase; Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate. | Glucose-6-phosphate isomerase; Functions in sugar metabolism in glycolysis and the Embden-Meyerhof pathways (EMP) and in gluconeogenesis; catalyzes reversible isomerization of glucose-6-phosphate to fructose-6-phosphate; member of PGI family; Belongs to the GPI family. | 0.984 |
AMN46112.1 | pgk | ACG33_03100 | ACG33_03110 | Transketolase; Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate. | Phosphoglycerate kinase; Belongs to the phosphoglycerate kinase family. | 0.938 |
AMN46112.1 | tpiA | ACG33_03100 | ACG33_06860 | Transketolase; Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate. | Triosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family. | 0.934 |
AMN46115.1 | AMN46112.1 | ACG33_03115 | ACG33_03100 | Pyruvate kinase; Catalyzes the formation of phosphoenolpyruvate from pyruvate; Belongs to the pyruvate kinase family. | Transketolase; Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate. | 0.979 |
AMN46115.1 | AMN47646.1 | ACG33_03115 | ACG33_11150 | Pyruvate kinase; Catalyzes the formation of phosphoenolpyruvate from pyruvate; Belongs to the pyruvate kinase family. | Malate dehydrogenase. | 0.968 |
AMN46115.1 | eno | ACG33_03115 | ACG33_09515 | Pyruvate kinase; Catalyzes the formation of phosphoenolpyruvate from pyruvate; Belongs to the pyruvate kinase family. | Enolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis. | 0.994 |
AMN46115.1 | gapA | ACG33_03115 | ACG33_03105 | Pyruvate kinase; Catalyzes the formation of phosphoenolpyruvate from pyruvate; Belongs to the pyruvate kinase family. | Glyceraldehyde-3-phosphate dehydrogenase; Required for glycolysis; catalyzes the formation of 3-phospho-D-glyceroyl phosphate from D-glyceraldehyde 3-phosphate; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. | 0.971 |
AMN46115.1 | gpmA | ACG33_03115 | ACG33_02445 | Pyruvate kinase; Catalyzes the formation of phosphoenolpyruvate from pyruvate; Belongs to the pyruvate kinase family. | Phosphoglyceromutase; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate; Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily. | 0.933 |
AMN46115.1 | pfp | ACG33_03115 | ACG33_03025 | Pyruvate kinase; Catalyzes the formation of phosphoenolpyruvate from pyruvate; Belongs to the pyruvate kinase family. | 6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP- PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions. | 0.968 |
AMN46115.1 | pgi | ACG33_03115 | ACG33_04735 | Pyruvate kinase; Catalyzes the formation of phosphoenolpyruvate from pyruvate; Belongs to the pyruvate kinase family. | Glucose-6-phosphate isomerase; Functions in sugar metabolism in glycolysis and the Embden-Meyerhof pathways (EMP) and in gluconeogenesis; catalyzes reversible isomerization of glucose-6-phosphate to fructose-6-phosphate; member of PGI family; Belongs to the GPI family. | 0.987 |
AMN46115.1 | pgk | ACG33_03115 | ACG33_03110 | Pyruvate kinase; Catalyzes the formation of phosphoenolpyruvate from pyruvate; Belongs to the pyruvate kinase family. | Phosphoglycerate kinase; Belongs to the phosphoglycerate kinase family. | 0.982 |
AMN46115.1 | tpiA | ACG33_03115 | ACG33_06860 | Pyruvate kinase; Catalyzes the formation of phosphoenolpyruvate from pyruvate; Belongs to the pyruvate kinase family. | Triosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family. | 0.955 |
AMN47646.1 | AMN46112.1 | ACG33_11150 | ACG33_03100 | Malate dehydrogenase. | Transketolase; Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate. | 0.496 |
AMN47646.1 | AMN46115.1 | ACG33_11150 | ACG33_03115 | Malate dehydrogenase. | Pyruvate kinase; Catalyzes the formation of phosphoenolpyruvate from pyruvate; Belongs to the pyruvate kinase family. | 0.968 |