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dut protein (Erwinia tasmaniensis) - STRING interaction network
"dut" - Deoxyuridine 5'-triphosphate nucleotidohydrolase in Erwinia tasmaniensis
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second shell of interactors
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proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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dutDeoxyuridine 5’-triphosphate nucleotidohydrolase; This enzyme is involved in nucleotide metabolism- it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA (152 aa)    
Predicted Functional Partners:
thyA
Thymidylate synthase; Provides the sole de novo source of dTMP for DNA biosynthesis (264 aa)
   
  0.987
nrdA
Ribonucleotide-diphosphate reductase subunit alpha; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (761 aa)
   
 
  0.984
nrdE
Ribonucleoside-diphosphate reductase 2 subunit alpha; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (693 aa)
   
 
  0.984
dnaN
DNA polymerase III subunit beta; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3’ to 5’ exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (366 aa)
   
 
  0.983
tmk
Thymidylate kinase; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis (210 aa)
   
 
  0.966
tdk
Thymidine kinase (207 aa)
     
 
  0.943
dfp
Flavoprotein affecting synthesis of DNA and pantothenate metabolism (404 aa)
   
        0.942
dcd
Deoxycytidine triphosphate deaminase (193 aa)
   
   
  0.913
ndk
Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate (143 aa)
     
 
    0.912
nrdD
Anaerobic ribonucleoside triphosphate reductase (712 aa)
       
  0.909
Your Current Organism:
Erwinia tasmaniensis
NCBI taxonomy Id: 465817
Other names: E. tasmaniensis, E. tasmaniensis Et1/99, Erwinia tasmaniensis, Erwinia tasmaniensis Et1/99, Erwinia tasmaniensis Geider et al. 2006, Erwinia tasmaniensis str. Et1/99, Erwinia tasmaniensis strain Et1/99
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