Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
dfpFlavoprotein affecting synthesis of DNA and pantothenate metabolism; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. (404 aa)    
Predicted Functional Partners:
dut
Deoxyuridine 5'-triphosphate nucleotidohydrolase (dUTP pyrophosphatase); This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA; Belongs to the dUTPase family.
 
  
 0.981
coaD
Phosphopantetheine adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family.
 
 
 0.962
coaA
Pantothenate kinase; silverDB:etchr00146.
   
 
 0.926
acpH
Acyl carrier protein phosphodiesterase; silverDB:etchr02529.
     
  0.900
mazG
Hypothetical protein MazG; silverDB:etchr02710.
     
  0.900
panC
Pantoate-beta-alanine ligase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family.
  
  
  0.846
metC
Cystathionine beta-lyase; silverDB:etchr00449.
  
 
  0.829
cysK
Cysteine synthase A; silverDB:etchr01091; Belongs to the cysteine synthase/cystathionine beta- synthase family.
    
  0.808
ETA_27490
Cysteine synthase A; silverDB:etchr02737; Belongs to the cysteine synthase/cystathionine beta- synthase family.
    
  0.808
ETA_14770
Aminotransferase, class I and II; silverDB:etchr01467.
    
  0.801
Your Current Organism:
Erwinia tasmaniensis
NCBI taxonomy Id: 465817
Other names: E. tasmaniensis Et1/99, Erwinia tasmaniensis Et1/99, Erwinia tasmaniensis str. Et1/99, Erwinia tasmaniensis strain Et1/99
Server load: low (16%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.