STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ETA_03370Penicillin-binding protein 4 precursor; silverDB:etchr00336. (477 aa)    
Predicted Functional Partners:
mrcA
Penicillin-binding protein 1A; silverDB:etchr03198.
  
  
 0.936
mrcB
Penicillin-binding protein 1B; Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross- linking of the peptide subunits).
     
 0.925
mrdA
Penicillin-binding protein 2; Catalyzes cross-linking of the peptidoglycan cell wall. Belongs to the transpeptidase family. MrdA subfamily.
     
 0.925
dacD
Penicillin-binding protein 6B precursor (D-alanyl-D-alanine carboxypeptidase); silverDB:etchr01353; Belongs to the peptidase S11 family.
     
 0.924
ftsI
Peptidoglycan synthetase; Catalyzes cross-linking of the peptidoglycan cell wall at the division septum; Belongs to the transpeptidase family. FtsI subfamily.
     
 0.923
ftsI-2
Peptidoglycan synthetase; Catalyzes cross-linking of the peptidoglycan cell wall at the division septum; Belongs to the transpeptidase family. FtsI subfamily.
     
 0.923
dacC
D-alanyl-D-alanine carboxypeptidase; silverDB:etchr02174; Belongs to the peptidase S11 family.
     
 0.912
dacA
Penicillin-binding protein 5; silverDB:etchr02344; Belongs to the peptidase S11 family.
     
 0.912
mtgA
Monofunctional biosynthetic peptidoglycan transglycosylase; Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors; Belongs to the glycosyltransferase 51 family.
     
 0.911
pmrB
Two-component system sensor protein; silverDB:etchr00334.
  
  
 0.895
Your Current Organism:
Erwinia tasmaniensis
NCBI taxonomy Id: 465817
Other names: E. tasmaniensis Et1/99, Erwinia tasmaniensis Et1/99, Erwinia tasmaniensis str. Et1/99, Erwinia tasmaniensis strain Et1/99
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