Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
metCCystathionine beta-lyase; silverDB:etchr00449. (396 aa)    
Predicted Functional Partners:
cysK
Cysteine synthase A; silverDB:etchr01091; Belongs to the cysteine synthase/cystathionine beta- synthase family.
 
 0.967
ETA_27490
Cysteine synthase A; silverDB:etchr02737; Belongs to the cysteine synthase/cystathionine beta- synthase family.
 
 0.963
metB
Cystathionine gamma-synthase; silverDB:etchr00126.
  
 
 
0.956
sseA
3-mercaptopyruvate:cyanide sulfurtransferase; silverDB:etchr01014.
 
 
 0.949
metE
5-methyltetrahydropteroyltriglutamate-- homocysteine methyltransferase; Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation; Belongs to the vitamin-B12 independent methionine synthase family.
  
 
 0.946
ETA_10400
Methionine synthase; silverDB:etchr01031.
  
 
 0.946
luxS
Autoinducer-2 production protein; Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD). Belongs to the LuxS family.
 
 
 0.941
ETA_14770
Aminotransferase, class I and II; silverDB:etchr01467.
 
 
 0.937
dcyD
D-cysteine desulfhydrase; silverDB:etchr01418.
     
 0.925
metL
Bifunctional aspartokinase/homoserine dehydrogenase II (AKII-HDII); silverDB:etchr00127; In the C-terminal section; belongs to the homoserine dehydrogenase family.
  
 
 0.920
Your Current Organism:
Erwinia tasmaniensis
NCBI taxonomy Id: 465817
Other names: E. tasmaniensis Et1/99, Erwinia tasmaniensis Et1/99, Erwinia tasmaniensis str. Et1/99, Erwinia tasmaniensis strain Et1/99
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