STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
exbBBiopolymer transport ExbB protein; silverDB:etchr00450. (244 aa)    
Predicted Functional Partners:
exbD
Biopolymer transport ExbD protein; silverDB:etchr00451.
 
 
 0.999
tolR
TolR colicin import membrane protein; Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity. Required, with TolQ, for the proton motive force-dependent activation of TolA and for TolA-Pal interaction.
 
 
 0.937
tonB
Periplasmic protein; Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy-requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins. Belongs to the TonB family.
  
 
 0.906
pal
Peptidoglycan-associated lipoprotein Pal, OmpA family of porins; Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
 
   
 0.694
tolB
Protein TolB (translocation of group A colicins); Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity. TolB occupies a key intermediary position in the Tol-Pal system because it communicates directly with both membrane-embedded components, Pal in the outer membrane and TolA in the inner membrane.
 
  
 0.665
fhuA
Ferrichrome iron receptor; silverDB:etchr00866.
 
  
 0.628
metC
Cystathionine beta-lyase; silverDB:etchr00449.
 
     0.611
lolE
Lipoprotein releasing system transmembrane protein; silverDB:etchr01966.
 
    0.531
ETA_19790
ABC-type transport system, involved in lipoprotein release, permease component; silverDB:etchr01968.
 
    0.515
fecI
RNA polymerase sigma factor FecI; silverDB:etchr03020; Belongs to the sigma-70 factor family. ECF subfamily.
  
  
 0.466
Your Current Organism:
Erwinia tasmaniensis
NCBI taxonomy Id: 465817
Other names: E. tasmaniensis Et1/99, Erwinia tasmaniensis Et1/99, Erwinia tasmaniensis str. Et1/99, Erwinia tasmaniensis strain Et1/99
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.