Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
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Co-occurrence
Co-expression
Experiments
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[Homology]
Score
trpRTrp operon repressor; This protein is an aporepressor. When complexed with L- tryptophan it binds the operator region of the trp operon (5'- ACTAGT-'3') and prevents the initiation of transcription. The complex also regulates trp repressor biosynthesis by binding to its regulatory region. (110 aa)    
Predicted Functional Partners:
lepB
Signal peptidase I; silverDB:etchr00982; Belongs to the peptidase S26 family.
   
    0.817
ETA_32790
Putative inner membrane protein; silverDB:etchr03265.
  
    0.814
ycbG
Conserved hypothetical protein (DUF1047); Required for spatial organization of the terminus region of the chromosome (Ter macrodomain) during the cell cycle. Prevents early segregation of duplicated Ter macrodomains during cell division. Binds specifically to matS, which is a 13 bp signature motif repeated within the Ter macrodomain.
  
     0.769
ycdY
Conserved hypothetical protein YcdY; silverDB:etchr01433.
  
    0.741
ETA_15280
Conserved hypothetical protein; silverDB:etchr01518; Belongs to the UPF0181 family.
  
     0.709
yacL
Conserved hypothetical protein YacL; silverDB:etchr00820; Belongs to the UPF0231 family.
  
     0.708
mukE
Chromosome partition protein; Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF.
  
     0.707
slt
Soluble lytic murein transglycosylase; silverDB:etchr00682.
 
     0.705
ETA_28430
Putative exported protein; silverDB:etchr02831.
  
     0.697
yniB
Hypothetical protein YniB; silverDB:etchr01834.
  
     0.687
Your Current Organism:
Erwinia tasmaniensis
NCBI taxonomy Id: 465817
Other names: E. tasmaniensis Et1/99, Erwinia tasmaniensis Et1/99, Erwinia tasmaniensis str. Et1/99, Erwinia tasmaniensis strain Et1/99
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