Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
carBCarbamoyl-phosphate synthase large chain; silverDB:etchr00710; Belongs to the CarB family. (1074 aa)    
Predicted Functional Partners:
pyrB
Aspartate transcarbamylase catalytic subunit PyrB; silverDB:etchr00363; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.
 
 0.999
carA
Carbamoyl-phosphate synthase small chain; silverDB:etchr00709; Belongs to the CarA family.
 0.999
argG
Argininosuccinate synthase; silverDB:etchr00135; Belongs to the argininosuccinate synthase family. Type 1 subfamily.
 
 0.988
purF
Amidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine; In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.
 
 
 0.988
ETA_03080
Glutamate synthase (NADPH); silverDB:etchr00307.
  
 
 0.985
argI
Ornithine carbamoyltransferase; Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
 
 
 0.979
pyrI
Aspartate transcarbamylase regulatory subunit PyrI; Involved in allosteric regulation of aspartate carbamoyltransferase.
  
 
 0.973
pyrD
Dihydroorotate dehydrogenase; Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.
 
 
 0.963
pyrE
Orotate phosphoribosyltransferase (OPRTase); Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
  
 
 0.945
glmS
Glucosamine-fructose-6-phosphate aminotransferase [isomerizing]; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
   
 0.936
Your Current Organism:
Erwinia tasmaniensis
NCBI taxonomy Id: 465817
Other names: E. tasmaniensis Et1/99, Erwinia tasmaniensis Et1/99, Erwinia tasmaniensis str. Et1/99, Erwinia tasmaniensis strain Et1/99
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