node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
dxs | ppnK | ETA_25270 | ETA_09770 | 1-deoxy-D-xylulose 5-phosphate synthase; Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D- xylulose-5-phosphate (DXP); Belongs to the transketolase family. DXPS subfamily. | Probable inorganic polyphosphate/ATP-NAD kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. | 0.655 |
grpE | ppnK | ETA_09780 | ETA_09770 | Heat shock protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-depen [...] | Probable inorganic polyphosphate/ATP-NAD kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. | 0.855 |
grpE | recN | ETA_09780 | ETA_09760 | Heat shock protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-depen [...] | Protein used in recombination and DNA repair (DNA repair protein RecN); May be involved in recombinational repair of damaged DNA. | 0.586 |
mazG | nadD | ETA_27220 | ETA_23500 | Hypothetical protein MazG; silverDB:etchr02710. | Nicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). | 0.901 |
mazG | nadE | ETA_27220 | ETA_18510 | Hypothetical protein MazG; silverDB:etchr02710. | NH(3)-dependent NAD(+) synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source. | 0.900 |
mazG | nadR | ETA_27220 | ETA_06740 | Hypothetical protein MazG; silverDB:etchr02710. | Transcriptional regulator NadR; silverDB:etchr00666. | 0.905 |
mazG | npdA | ETA_27220 | ETA_19750 | Hypothetical protein MazG; silverDB:etchr02710. | NAD-dependent deacetylase; silverDB:etchr01964; Belongs to the sirtuin family. Class III subfamily. | 0.900 |
mazG | nudC | ETA_27220 | ETA_01730 | Hypothetical protein MazG; silverDB:etchr02710. | NADH pyrophosphatase; silverDB:etchr00172. | 0.911 |
mazG | ppnK | ETA_27220 | ETA_09770 | Hypothetical protein MazG; silverDB:etchr02710. | Probable inorganic polyphosphate/ATP-NAD kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. | 0.900 |
mazG | udhA | ETA_27220 | ETA_01400 | Hypothetical protein MazG; silverDB:etchr02710. | Soluble pyridine nucleotide transhydrogenase; Conversion of NADPH, generated by peripheral catabolic pathways, to NADH, which can enter the respiratory chain for energy generation; Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family. | 0.906 |
nadD | mazG | ETA_23500 | ETA_27220 | Nicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). | Hypothetical protein MazG; silverDB:etchr02710. | 0.901 |
nadD | nadE | ETA_23500 | ETA_18510 | Nicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). | NH(3)-dependent NAD(+) synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source. | 0.940 |
nadD | nadR | ETA_23500 | ETA_06740 | Nicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). | Transcriptional regulator NadR; silverDB:etchr00666. | 0.942 |
nadD | npdA | ETA_23500 | ETA_19750 | Nicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). | NAD-dependent deacetylase; silverDB:etchr01964; Belongs to the sirtuin family. Class III subfamily. | 0.934 |
nadD | nudC | ETA_23500 | ETA_01730 | Nicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). | NADH pyrophosphatase; silverDB:etchr00172. | 0.906 |
nadD | ppnK | ETA_23500 | ETA_09770 | Nicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). | Probable inorganic polyphosphate/ATP-NAD kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. | 0.947 |
nadD | udhA | ETA_23500 | ETA_01400 | Nicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). | Soluble pyridine nucleotide transhydrogenase; Conversion of NADPH, generated by peripheral catabolic pathways, to NADH, which can enter the respiratory chain for energy generation; Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family. | 0.900 |
nadE | mazG | ETA_18510 | ETA_27220 | NH(3)-dependent NAD(+) synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source. | Hypothetical protein MazG; silverDB:etchr02710. | 0.900 |
nadE | nadD | ETA_18510 | ETA_23500 | NH(3)-dependent NAD(+) synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source. | Nicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). | 0.940 |
nadE | nadR | ETA_18510 | ETA_06740 | NH(3)-dependent NAD(+) synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source. | Transcriptional regulator NadR; silverDB:etchr00666. | 0.952 |