STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ycfCConserved hypothetical protein YcfC; silverDB:etchr01957. (214 aa)    
Predicted Functional Partners:
trmU
tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase; Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA(Lys), tRNA(Glu) and tRNA(Gln), leading to the formation of s(2)U34, the first step of tRNA-mnm(5)s(2)U34 synthesis. Sulfur is provided by IscS, via a sulfur-relay system. Binds ATP and its substrate tRNAs; Belongs to the MnmA/TRMU family.
  
  
 0.972
purB
Adenylosuccinate lyase; silverDB:etchr01958; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.
  
    0.845
nudJ
Putative MutT family protein; silverDB:etchr01955; Belongs to the Nudix hydrolase family. NudJ subfamily.
 
     0.834
rnt
Ribonuclease T; Trims short 3' overhangs of a variety of RNA species, leaving a one or two nucleotide 3' overhang. Responsible for the end-turnover of tRNA: specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A). Also appears to be involved in tRNA biosynthesis.
  
    0.706
ETA_15380
Conserved hypothetical protein (DUF709); silverDB:etchr01528.
  
    0.694
ycfD
Conserved hypothetical protein YcfD; silverDB:etchr01961.
 
  
 0.638
yceD
Conserved hypothetical protein YceD; silverDB:etchr02015.
  
    0.636
dsbC
Protein disulfide isomerase II; Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process; Belongs to the thioredoxin family. DsbC subfamily.
  
     0.627
phoP
Two-component response regulator of virulence determinants; silverDB:etchr01959.
       0.563
phoQ
Virulence sensor histidine kinase; silverDB:etchr01960.
       0.563
Your Current Organism:
Erwinia tasmaniensis
NCBI taxonomy Id: 465817
Other names: E. tasmaniensis Et1/99, Erwinia tasmaniensis Et1/99, Erwinia tasmaniensis str. Et1/99, Erwinia tasmaniensis strain Et1/99
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.