Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ycfDConserved hypothetical protein YcfD; silverDB:etchr01961. (382 aa)    
Predicted Functional Partners:
rplP
50S ribosomal protein L16; Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs; Belongs to the universal ribosomal protein uL16 family.
    
 
 0.686
yhdP
Conserved hypothetical protein YhdP; silverDB:etchr00288.
  
     0.651
bacA
Similar to bacitracin synthetase 1 (BA1), protein contains non-ribosomal peptide synthetase modules; silverDB:etchr02904.
       0.632
ycfC
Conserved hypothetical protein YcfC; silverDB:etchr01957.
 
  
 0.592
phoP
Two-component response regulator of virulence determinants; silverDB:etchr01959.
       0.566
phoQ
Virulence sensor histidine kinase; silverDB:etchr01960.
       0.566
trmU
tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase; Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA(Lys), tRNA(Glu) and tRNA(Gln), leading to the formation of s(2)U34, the first step of tRNA-mnm(5)s(2)U34 synthesis. Sulfur is provided by IscS, via a sulfur-relay system. Binds ATP and its substrate tRNAs; Belongs to the MnmA/TRMU family.
     
 0.520
purB
Adenylosuccinate lyase; silverDB:etchr01958; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.
     
 0.477
ETA_32140
Putative membrane protein; silverDB:etchr03200.
  
     0.457
rcsF
Regulator in colanic acid synthesis; Essential component of the Rcs signaling system, which controls transcription of numerous genes. Plays a role in signal transduction from the cell surface to the histidine kinase RcsC. May detect outer membrane defects; Belongs to the RcsF family.
  
     0.454
Your Current Organism:
Erwinia tasmaniensis
NCBI taxonomy Id: 465817
Other names: E. tasmaniensis Et1/99, Erwinia tasmaniensis Et1/99, Erwinia tasmaniensis str. Et1/99, Erwinia tasmaniensis strain Et1/99
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