| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ETA_03070 | cysJ | ETA_03070 | ETA_27110 | Sulfite reductase; Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L-cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH -> FAD -> FMN to the hemoprotein component. | Sulfite reductase [NADPH] flavoprotein alpha-component; Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L-cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH -> FAD -> FMN to the hemoprotein component. Belongs to the NADPH-dependent sulphite reductase flavoprotein subunit CysJ family. In the N-terminal section; belongs to the flavodoxin family. | 0.911 |
| ETA_03070 | ycbX | ETA_03070 | ETA_21130 | Sulfite reductase; Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L-cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH -> FAD -> FMN to the hemoprotein component. | Conserved hypothetical protein YcbX; silverDB:etchr02101. | 0.757 |
| ETA_21080 | uup | ETA_21080 | ETA_21110 | Putative lipoprotein protein; silverDB:etchr02096. | ABC transporter ATP-binding protein uup; silverDB:etchr02099. | 0.865 |
| ETA_21080 | ycbX | ETA_21080 | ETA_21130 | Putative lipoprotein protein; silverDB:etchr02096. | Conserved hypothetical protein YcbX; silverDB:etchr02101. | 0.620 |
| ETA_21080 | ycbY | ETA_21080 | ETA_21120 | Putative lipoprotein protein; silverDB:etchr02096. | Conserved hypothetical protein YcbY; Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA. Belongs to the methyltransferase superfamily. RlmKL family. | 0.865 |
| bacA | fumA | ETA_29170 | ETA_19280 | Similar to bacitracin synthetase 1 (BA1), protein contains non-ribosomal peptide synthetase modules; silverDB:etchr02904. | Fumarase A; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family. | 0.478 |
| bacA | gntY | ETA_29170 | ETA_32280 | Similar to bacitracin synthetase 1 (BA1), protein contains non-ribosomal peptide synthetase modules; silverDB:etchr02904. | Putative membrane-bound protein GntY; Involved in iron-sulfur cluster biogenesis. Binds a 4Fe-4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe/S proteins. Could also act as a scaffold/chaperone for damaged Fe/S proteins. | 0.723 |
| bacA | iscS | ETA_29170 | ETA_10200 | Similar to bacitracin synthetase 1 (BA1), protein contains non-ribosomal peptide synthetase modules; silverDB:etchr02904. | Cysteine desulfurase (NifS protein homolog); Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily. | 0.663 |
| bacA | nuoC | ETA_29170 | ETA_12060 | Similar to bacitracin synthetase 1 (BA1), protein contains non-ribosomal peptide synthetase modules; silverDB:etchr02904. | NADH dehydrogenase I C/D; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; In the N-terminal section; belongs to the complex I 30 kDa subunit family. | 0.995 |
| bacA | ycbX | ETA_29170 | ETA_21130 | Similar to bacitracin synthetase 1 (BA1), protein contains non-ribosomal peptide synthetase modules; silverDB:etchr02904. | Conserved hypothetical protein YcbX; silverDB:etchr02101. | 0.700 |
| cysJ | ETA_03070 | ETA_27110 | ETA_03070 | Sulfite reductase [NADPH] flavoprotein alpha-component; Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L-cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH -> FAD -> FMN to the hemoprotein component. Belongs to the NADPH-dependent sulphite reductase flavoprotein subunit CysJ family. In the N-terminal section; belongs to the flavodoxin family. | Sulfite reductase; Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L-cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH -> FAD -> FMN to the hemoprotein component. | 0.911 |
| cysJ | ycbX | ETA_27110 | ETA_21130 | Sulfite reductase [NADPH] flavoprotein alpha-component; Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L-cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH -> FAD -> FMN to the hemoprotein component. Belongs to the NADPH-dependent sulphite reductase flavoprotein subunit CysJ family. In the N-terminal section; belongs to the flavodoxin family. | Conserved hypothetical protein YcbX; silverDB:etchr02101. | 0.757 |
| fumA | bacA | ETA_19280 | ETA_29170 | Fumarase A; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family. | Similar to bacitracin synthetase 1 (BA1), protein contains non-ribosomal peptide synthetase modules; silverDB:etchr02904. | 0.478 |
| fumA | nuoC | ETA_19280 | ETA_12060 | Fumarase A; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family. | NADH dehydrogenase I C/D; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; In the N-terminal section; belongs to the complex I 30 kDa subunit family. | 0.450 |
| fumA | ycbX | ETA_19280 | ETA_21130 | Fumarase A; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family. | Conserved hypothetical protein YcbX; silverDB:etchr02101. | 0.665 |
| gntY | bacA | ETA_32280 | ETA_29170 | Putative membrane-bound protein GntY; Involved in iron-sulfur cluster biogenesis. Binds a 4Fe-4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe/S proteins. Could also act as a scaffold/chaperone for damaged Fe/S proteins. | Similar to bacitracin synthetase 1 (BA1), protein contains non-ribosomal peptide synthetase modules; silverDB:etchr02904. | 0.723 |
| gntY | iscS | ETA_32280 | ETA_10200 | Putative membrane-bound protein GntY; Involved in iron-sulfur cluster biogenesis. Binds a 4Fe-4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe/S proteins. Could also act as a scaffold/chaperone for damaged Fe/S proteins. | Cysteine desulfurase (NifS protein homolog); Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily. | 0.962 |
| gntY | nuoC | ETA_32280 | ETA_12060 | Putative membrane-bound protein GntY; Involved in iron-sulfur cluster biogenesis. Binds a 4Fe-4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe/S proteins. Could also act as a scaffold/chaperone for damaged Fe/S proteins. | NADH dehydrogenase I C/D; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; In the N-terminal section; belongs to the complex I 30 kDa subunit family. | 0.561 |
| gntY | ycbX | ETA_32280 | ETA_21130 | Putative membrane-bound protein GntY; Involved in iron-sulfur cluster biogenesis. Binds a 4Fe-4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe/S proteins. Could also act as a scaffold/chaperone for damaged Fe/S proteins. | Conserved hypothetical protein YcbX; silverDB:etchr02101. | 0.793 |
| iscS | bacA | ETA_10200 | ETA_29170 | Cysteine desulfurase (NifS protein homolog); Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily. | Similar to bacitracin synthetase 1 (BA1), protein contains non-ribosomal peptide synthetase modules; silverDB:etchr02904. | 0.663 |
