Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
nfsAOxygen-insensitive NADPH nitroreductase (Modulator of drug activity A); silverDB:etchr02167; Belongs to the flavin oxidoreductase frp family. (240 aa)    
Predicted Functional Partners:
nemA
N-ethylmaleimide reductase; silverDB:etchr01790.
  
 
 0.901
ETA_30430
NADH-dependent flavin oxidoreductase, Old Yellow Enzyme family; silverDB:etchr03030.
  
 
 0.901
ETA_21800
Hypothetical protein; silverDB:etchr02168.
  
  
 0.899
bacA
Similar to bacitracin synthetase 1 (BA1), protein contains non-ribosomal peptide synthetase modules; silverDB:etchr02904.
  
 
 0.772
yadH
ABC transporter integral membrane protein; silverDB:etchr00845.
  
  
 0.574
grxA
silverDB:etchr02169.
  
  
 0.560
ycaO
Conserved hypothetical protein YcaO; silverDB:etchr02134.
  
  
 0.559
ETA_03080
Glutamate synthase (NADPH); silverDB:etchr00307.
     
 0.555
birA
Bifunctional protein: biotin operon repressor and biotin-[acetyl-CoA carboxylase] synthetase; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio-5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon.
  
    0.541
ETA_21780
Conserved hypothetical protein; silverDB:etchr02166.
     
 0.480
Your Current Organism:
Erwinia tasmaniensis
NCBI taxonomy Id: 465817
Other names: E. tasmaniensis Et1/99, Erwinia tasmaniensis Et1/99, Erwinia tasmaniensis str. Et1/99, Erwinia tasmaniensis strain Et1/99
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