Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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ppnPConserved hypothetical protein; Catalyzes the phosphorolysis of diverse nucleosides, yielding D-ribose 1-phosphate and the respective free bases. Can use uridine, adenosine, guanosine, cytidine, thymidine, inosine and xanthosine as substrates. Also catalyzes the reverse reactions. (96 aa)    
Predicted Functional Partners:
udp
Uridine phosphorylase; Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1-phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis. Belongs to the PNP/UDP phosphorylase family.
     
 0.923
deoD
Purine nucleoside phosphorylase deoD-type; silverDB:etchr00661.
     
 0.923
ushA
UshA protein (UDP-sugar hydrolase and 5'-nucleotidase) (EC 3.6.1.45; silverDB:etchr02448; Belongs to the 5'-nucleotidase family.
     
 0.923
deoA
Thymidine phosphorylase; The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis. Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family.
     
 0.922
add
Adenosine deaminase; silverDB:etchr01754; Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. Adenosine deaminase subfamily.
     
 0.907
cpdB
2',3'-cyclic-nucleotide 2'-phosphodiesterase; silverDB:etchr02934; Belongs to the 5'-nucleotidase family.
     
 0.904
udk
Uridine kinase; silverDB:etchr01307.
     
 0.903
apt
Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
     
 0.903
yjjG
Nucleoside 5'-monophosphate phosphohydrolase; silverDB:etchr00602.
     
  0.900
hpt
Hypoxanthine phosphoribosyltransferase; silverDB:etchr00842; Belongs to the purine/pyrimidine phosphoribosyltransferase family.
     
  0.900
Your Current Organism:
Erwinia tasmaniensis
NCBI taxonomy Id: 465817
Other names: E. tasmaniensis Et1/99, Erwinia tasmaniensis Et1/99, Erwinia tasmaniensis str. Et1/99, Erwinia tasmaniensis strain Et1/99
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