Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ETA_28320Conserved hypothetical protein (DUF179); silverDB:etchr02820; Belongs to the UPF0301 (AlgH) family. (187 aa)    
Predicted Functional Partners:
yqgF
Putative Holliday junction resolvase; Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA; Belongs to the YqgF HJR family.
  
  
 0.966
rimK
Glutathione synthase/Ribosomal protein S6 modification enzyme(glutaminyl transferase); silverDB:etchr02819; Belongs to the prokaryotic GSH synthase family.
 
   
 0.886
nadR
Transcriptional regulator NadR; silverDB:etchr00666.
   
    0.866
nrdE
Ribonucleoside-diphosphate reductase 2, alpha subunit; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.
   
 0.854
nrdA
Ribonucleoside-diphosphate reductase 1 alpha subunit; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.
   
 0.854
dnaN
DNA polymerase III subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]
  
 
 0.682
yggJ
Conserved hypothetical protein YggJ; Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.
     
 0.524
ETA_28340
Alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen; silverDB:etchr02822.
       0.511
ccmG
Cytochrome c biogenesis protein CcmG (Thiol:disulfide interchange protein DsbE); silverDB:etchr01134.
   
 
  0.508
nuoC
NADH dehydrogenase I C/D; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; In the N-terminal section; belongs to the complex I 30 kDa subunit family.
  
    0.477
Your Current Organism:
Erwinia tasmaniensis
NCBI taxonomy Id: 465817
Other names: E. tasmaniensis Et1/99, Erwinia tasmaniensis Et1/99, Erwinia tasmaniensis str. Et1/99, Erwinia tasmaniensis strain Et1/99
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