Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-occurrence
Co-expression
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[Homology]
Score
mclAPutative microcin L transport protein; silverDB:etchr03335. (427 aa)    
Predicted Functional Partners:
mchF
Probable microcin H47 secretion ATP-binding protein; silverDB:etchr03336.
 
 
 0.990
tolC
Outer membrane protein TolC; silverDB:etchr00432.
 
 
 0.884
ETA_30120
ABC transporter (Peptidase C39), probable bacteriocin; silverDB:etchr02999.
  
 
 0.861
macB
Macrolide-specific ABC-type efflux carrier; silverDB:etchr02997; Belongs to the ABC transporter superfamily. Macrolide exporter (TC 3.A.1.122) family.
  
  
 0.771
lapB
Predicted N-acetylglucosaminyl transferase, similar to conserved hypothetical protein YciM; Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane; Belongs to the LapB family.
  
   
 0.710
ftsN
Cell division protein; Essential cell division protein that activates septal peptidoglycan synthesis and constriction of the cell. Acts on both sides of the membrane, via interaction with FtsA in the cytoplasm and interaction with the FtsQBL complex in the periplasm. These interactions may induce a conformational switch in both FtsA and FtsQBL, leading to septal peptidoglycan synthesis by FtsI and associated synthases.
  
    0.655
holD
DNA polymerase III, psi subunit; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The exact function of the psi subunit is unknown.
  
     0.652
barA
Signal transduction histidine-protein kinase BarA; silverDB:etchr02713.
 
   
 0.624
metJ
Met repressor (Met regulon regulatory protein metJ); This regulatory protein, when combined with SAM (S- adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis; Belongs to the MetJ family.
  
   
 0.598
ETA_05870
Tail fiber assembly protein; silverDB:etchr00582.
  
     0.595
Your Current Organism:
Erwinia tasmaniensis
NCBI taxonomy Id: 465817
Other names: E. tasmaniensis Et1/99, Erwinia tasmaniensis Et1/99, Erwinia tasmaniensis str. Et1/99, Erwinia tasmaniensis strain Et1/99
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