STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ETA_33720Inosine/uridine-preferring nucleoside hydrolase; silverDB:etchr03358; Belongs to the IUNH family. (306 aa)    
Predicted Functional Partners:
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Adenosine deaminase; silverDB:etchr01754; Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. Adenosine deaminase subfamily.
 
 
 0.921
guaD
Guanine deaminase; Catalyzes the hydrolytic deamination of guanine, producing xanthine and ammonia; Belongs to the metallo-dependent hydrolases superfamily. ATZ/TRZ family.
 
  
 0.920
cpdB
2',3'-cyclic-nucleotide 2'-phosphodiesterase; silverDB:etchr02934; Belongs to the 5'-nucleotidase family.
  
 
  0.911
hpt
Hypoxanthine phosphoribosyltransferase; silverDB:etchr00842; Belongs to the purine/pyrimidine phosphoribosyltransferase family.
     
 0.910
gsk
Inosine-guanosine kinase; silverDB:etchr02451.
  
 
 0.907
apt
Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
     
 0.907
gpt
Xanthine phosphoribosyltransferase; Acts on guanine, xanthine and to a lesser extent hypoxanthine; Belongs to the purine/pyrimidine phosphoribosyltransferase family. XGPT subfamily.
     
 0.907
ushA
UshA protein (UDP-sugar hydrolase and 5'-nucleotidase) (EC 3.6.1.45; silverDB:etchr02448; Belongs to the 5'-nucleotidase family.
  
 
  0.905
amn
AMP nucleosidase; Catalyzes the hydrolysis of the N-glycosidic bond of AMP to form adenine and ribose 5-phosphate. Involved in regulation of AMP concentrations.
     
 0.904
pncA
Pyrazinamidase/nicotinamidase; silverDB:etchr01553.
     
 0.903
Your Current Organism:
Erwinia tasmaniensis
NCBI taxonomy Id: 465817
Other names: E. tasmaniensis Et1/99, Erwinia tasmaniensis Et1/99, Erwinia tasmaniensis str. Et1/99, Erwinia tasmaniensis strain Et1/99
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