STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Lmac_0052Putative chaperone-modulator protein CbpM. (104 aa)    
Predicted Functional Partners:
cbpA
DNA-binding protein DnaJ.
 
 
 0.995
dnaJ
Molecular chaperone DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, [...]
  
 
 0.766
Lmac_0884
Regulatory protein (GGDEF and EAL domains).
   
 0.740
Lmac_1019
Inner membrane protein/sensory box protein LssE.
    
 0.739
Lmac_2781
Chaperone protein DnaJ.
  
 
 0.734
Lmac_0703
Regulatory protein (GGDEF and EAL domains).
    
 0.698
Lmac_1132
Inner membrane protein.
    
 0.698
Lmac_1711
Sensory box protein (GGDEF domain/EAL domain).
    
 0.698
Lmac_0117
GGDEF domain-containing sensory box protein.
   
 0.663
Lmac_1260
Regulatory protein (GGDEF domain).
    
 0.623
Your Current Organism:
Legionella maceachernii
NCBI taxonomy Id: 466
Other names: ATCC 35300, CCUG 31116, CIP 103846, DSM 16642, JCM 7566, L. maceachernii, NCTC 11982, Tatlockia maceachernii, strain Px-1-G-2-E2
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