Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
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Co-occurrence
Co-expression
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[Homology]
Score
Lmac_0121IcmH (DotU). (261 aa)    
Predicted Functional Partners:
Lmac_0122
IcmF.
 
 
 0.989
pacL
Cation efflux transporter.
       0.746
Lmac_2668
Protein IcmE (DotG).
 
   
 0.654
Lmac_2814
Protein LvrA.
  
     0.587
Lmac_3045
Cysteine protease.
  
     0.554
icmV
Intracellular multiplication protein IcmV.
      
 0.531
lphA
LphA (DotK).
  
  
 0.529
dotA
Defect in organelle trafficking protein DotA.
  
     0.507
Lmac_1717
Hypothetical protein.
  
     0.503
zipA
Cell division protein ZipA; Essential cell division protein that stabilizes the FtsZ protofilaments by cross-linking them and that serves as a cytoplasmic membrane anchor for the Z ring. Also required for the recruitment to the septal ring of downstream cell division proteins. Belongs to the ZipA family.
  
     0.497
Your Current Organism:
Legionella maceachernii
NCBI taxonomy Id: 466
Other names: ATCC 35300, CCUG 31116, CIP 103846, DSM 16642, JCM 7566, L. maceachernii, NCTC 11982, Tatlockia maceachernii, strain Px-1-G-2-E2
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