STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Lmac_0306Aldo/keto reductase. (326 aa)    
Predicted Functional Partners:
Lmac_2714
D-xylose reductase III.
 
 0.765
hdaH
Histone deacetylase-like amidohydrolase.
   
  0.739
pdxH
Pyridoxamine 5'-phosphate oxidase; Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP).
     
 0.620
ugd
UDP-glucose 6-dehydrogenase.
   
 
  0.595
Lmac_0307
Estradiol 17-beta-dehydrogenase; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
       0.554
pksJ
Polyketide synthase, type I.
   
 0.517
Lmac_0449
Oxidoreductase.
  
 
 0.484
Lmac_1488
Methylmalonate-semialdehyde dehydrogenase.
  
 
 0.441
dnaK
Molecular chaperone DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family.
    
  0.438
yjeA
Endo-1,4-beta-xylanase.
    
  0.414
Your Current Organism:
Legionella maceachernii
NCBI taxonomy Id: 466
Other names: ATCC 35300, CCUG 31116, CIP 103846, DSM 16642, JCM 7566, L. maceachernii, NCTC 11982, Tatlockia maceachernii, strain Px-1-G-2-E2
Server load: low (20%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.