Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Lmac_0335Fimbrial protein, type IV pilin, PilE; Belongs to the N-Me-Phe pilin family. (136 aa)    
Predicted Functional Partners:
pilE
type-IV pilin.
 
  
 0.767
pilQ
Type IV pilus (Tfp) assembly protein PilQ.
 
   
 0.687
bolA
Regulator of penicillin binding proteins and beta lactamase transcription (morphogene); Belongs to the BolA/IbaG family.
       0.661
Lmac_0337
Hypothetical protein.
       0.560
asd
Aspartate-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family.
      
 0.531
Lmac_1521
Type 4 (IV) prepilin-like protein leader peptide processing enzyme PilD; Cleaves type-4 fimbrial leader sequence and methylates the N- terminal (generally Phe) residue.
 
   
 0.525
Lmac_0333
Acylphosphatase.
       0.500
Lmac_0334
Hypothetical protein.
       0.500
lspG
Type II secretory pathway protein LspG.
   
 0.462
pilC
Pilus assembly protein PilC.
 
   
 0.445
Your Current Organism:
Legionella maceachernii
NCBI taxonomy Id: 466
Other names: ATCC 35300, CCUG 31116, CIP 103846, DSM 16642, JCM 7566, L. maceachernii, NCTC 11982, Tatlockia maceachernii, strain Px-1-G-2-E2
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