STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
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[Homology]
Score
Lmac_03533-hydroxybutyrate dehydrogenase; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (260 aa)    
Predicted Functional Partners:
Lmac_0354
Acetoacetate decarboxylase.
 
  
  0.988
pksJ
Polyketide synthase, type I.
  
 0.957
Lmac_1430
Non-ribosomal peptide synthetase/polyketide synthetase.
  
 0.867
mvaB
hydroxymethylglutaryl-CoA lyase.
   
 
  0.859
acsA
acetyl-CoA synthetase.
     
  0.858
Lmac_2148
Polyketide synthase module.
  
 0.798
Lmac_2756
Non-ribosomal peptide synthetase; Belongs to the ATP-dependent AMP-binding enzyme family.
  
 0.715
Lmac_2147
Acetyltransferase.
  
 0.696
Lmac_2958
Patatin-like phospholipase.
  
     0.694
Lmac_1826
SAM-dependent O-methyltransferase.
 
      0.693
Your Current Organism:
Legionella maceachernii
NCBI taxonomy Id: 466
Other names: ATCC 35300, CCUG 31116, CIP 103846, DSM 16642, JCM 7566, L. maceachernii, NCTC 11982, Tatlockia maceachernii, strain Px-1-G-2-E2
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