Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
tesAAcyl-CoA thioesterase I precursor. (209 aa)    
Predicted Functional Partners:
egl
Endoglucanase precursor; Belongs to the glycosyl hydrolase 5 (cellulase A) family.
 
 
 0.846
Lmac_2499
Hypothetical protein.
  
 0.814
Lmac_2478
Hypothetical protein.
  
 0.810
avrBs3_2
Avirulence protein AvrBs3.
   
 0.762
Lmac_1474
Hypothetical protein.
   
 0.762
pksJ
Polyketide synthase, type I.
     
 0.652
Lmac_0748
Putative Heparan-alpha-glucosaminide N-acetyltransferase.
  
     0.535
birA
biotin-[acetylCoA carboxylase] holoenzyme synthetase and biotin operon repressor; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio-5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon.
      
 0.525
Lmac_2616
Alkaline phosphatase.
  
  
  0.522
lspG
Type II secretory pathway protein LspG.
       0.516
Your Current Organism:
Legionella maceachernii
NCBI taxonomy Id: 466
Other names: ATCC 35300, CCUG 31116, CIP 103846, DSM 16642, JCM 7566, L. maceachernii, NCTC 11982, Tatlockia maceachernii, strain Px-1-G-2-E2
Server load: low (18%) [HD]