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Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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Assay-based Predictions
experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
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Score
gidBGlucose inhibited division protein B GidB; Specifically methylates the N7 position of guanine in position 527 of 16S rRNA. (208 aa)    
Predicted Functional Partners:
gidA_1
tRNA uridine 5-carboxymethylaminomethyl modification enzyme GidA.
 
  
 0.974
parB_1
Chromosome partitioning protein parB; Belongs to the ParB family.
  
  
 0.933
trmE
tRNA modification GTPase TrmE; Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
  
  
 0.924
gidA_2
Glucose-inhibited division protein A.
  
  
 0.877
parA
Sporulation initiation inhibitor protein Soj.
  
  
 0.857
era
GTP-binding protein Era; An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
  
     0.600
parB_4
Chromosome partitioning protein ParB; Belongs to the ParB family.
  
  
 0.572
metG
Methionyl tRNA synthetase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
     
 0.561
parB_2
Chromosome partitioning protein ParB; Belongs to the ParB family.
  
  
 0.556
parB_3
Putative chromosome-partitioning protein ParB.
  
  
 0.556
Your Current Organism:
Legionella maceachernii
NCBI taxonomy Id: 466
Other names: ATCC 35300, CCUG 31116, CIP 103846, DSM 16642, JCM 7566, L. maceachernii, NCTC 11982, Tatlockia maceachernii, strain Px-1-G-2-E2
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