Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Lmac_0540SH3 domain of the SH3b1 type. (500 aa)    
Predicted Functional Partners:
ftsX
Cell division ATP transporter FtsX; Part of the ABC transporter FtsEX involved in cellular division; Belongs to the ABC-4 integral membrane protein family. FtsX subfamily.
   
 
 0.811
Lmac_1830
Hypothetical protein.
    
 
 0.733
amiB
N-acetylmuramoyl-L-alanine amidase.
  
 
 0.693
Lmac_1506
Hypothetical protein.
 
     0.620
Lmac_2367
Coiled-coil protein.
  
   
 0.610
yjeA
Endo-1,4-beta-xylanase.
 
   
 0.594
pksJ
Polyketide synthase, type I.
  
  
 0.594
Lmac_1869
Hypothetical protein.
  
    0.580
iraA
Small-molecule methyltransferase IraA.
  
     0.534
Lmac_3079
Coiled-coil protein.
  
     0.518
Your Current Organism:
Legionella maceachernii
NCBI taxonomy Id: 466
Other names: ATCC 35300, CCUG 31116, CIP 103846, DSM 16642, JCM 7566, L. maceachernii, NCTC 11982, Tatlockia maceachernii, strain Px-1-G-2-E2
Server load: low (30%) [HD]