| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| Lmac_0170 | apt | Lmac_0170 | Lmac_1025 | Inosine 5'-monophosphate dehydrogenase. | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | 0.475 |
| Lmac_0170 | gmk | Lmac_0170 | Lmac_2577 | Inosine 5'-monophosphate dehydrogenase. | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | 0.702 |
| Lmac_0170 | guaA | Lmac_0170 | Lmac_0556 | Inosine 5'-monophosphate dehydrogenase. | GMP synthase; Catalyzes the synthesis of GMP from XMP. | 0.998 |
| Lmac_0170 | guaB | Lmac_0170 | Lmac_0555 | Inosine 5'-monophosphate dehydrogenase. | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 0.883 |
| Lmac_0170 | ppt | Lmac_0170 | Lmac_1526 | Inosine 5'-monophosphate dehydrogenase. | Hypoxanthine-guanine phosphoribosyltransferase. | 0.876 |
| Lmac_0170 | purA | Lmac_0170 | Lmac_2869 | Inosine 5'-monophosphate dehydrogenase. | Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. | 0.979 |
| Lmac_0170 | purH | Lmac_0170 | Lmac_2842 | Inosine 5'-monophosphate dehydrogenase. | Bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase. | 0.983 |
| Lmac_0170 | pyrG | Lmac_0170 | Lmac_2197 | Inosine 5'-monophosphate dehydrogenase. | CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates. | 0.581 |
| apt | Lmac_0170 | Lmac_1025 | Lmac_0170 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | Inosine 5'-monophosphate dehydrogenase. | 0.475 |
| apt | gmk | Lmac_1025 | Lmac_2577 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | 0.706 |
| apt | guaA | Lmac_1025 | Lmac_0556 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | GMP synthase; Catalyzes the synthesis of GMP from XMP. | 0.980 |
| apt | guaB | Lmac_1025 | Lmac_0555 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 0.475 |
| apt | ppt | Lmac_1025 | Lmac_1526 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | Hypoxanthine-guanine phosphoribosyltransferase. | 0.633 |
| apt | purA | Lmac_1025 | Lmac_2869 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. | 0.809 |
| apt | purH | Lmac_1025 | Lmac_2842 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | Bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase. | 0.817 |
| apt | pyrG | Lmac_1025 | Lmac_2197 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates. | 0.454 |
| gmk | Lmac_0170 | Lmac_2577 | Lmac_0170 | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | Inosine 5'-monophosphate dehydrogenase. | 0.702 |
| gmk | apt | Lmac_2577 | Lmac_1025 | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | 0.706 |
| gmk | guaA | Lmac_2577 | Lmac_0556 | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | GMP synthase; Catalyzes the synthesis of GMP from XMP. | 0.977 |
| gmk | guaB | Lmac_2577 | Lmac_0555 | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 0.702 |
