Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Lmac_0635Coenzyme F420-reducing hydrogenase, alpha subunit. (423 aa)    
Predicted Functional Partners:
Lmac_0636
Sulfhydrogenase subunit delta.
 
 0.997
vhtD
Hydrogenase expression/formation protein.
 
  
 0.975
Lmac_0638
Hydrogenase subunit.
 
   
 0.969
hydG-2
Hydrogenase/sulfur reductase subunit gamma.
 
   
 0.968
hypF
Hydrogenase maturation protein HypF; Involved in the maturation of [NiFe] hydrogenases. Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of [NiFe]-hydrogenases. HypF functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide.
 
   
 0.839
hypE
Hydrogenase expression/formation protein HypE.
 
   
 0.815
hypD
Hydrogenase expression/formation protein HypD; Belongs to the HypD family.
 
   
 0.812
korA
2-oxoglutarate ferredoxin oxidoreductase subunit alpha.
    
 0.804
hypC
Hydrogenase expression/formation protein HypC.
 
   
 0.760
hypB
Hydrogenase nickel incorporation protein HypB.
     
 0.728
Your Current Organism:
Legionella maceachernii
NCBI taxonomy Id: 466
Other names: ATCC 35300, CCUG 31116, CIP 103846, DSM 16642, JCM 7566, L. maceachernii, NCTC 11982, Tatlockia maceachernii, strain Px-1-G-2-E2
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