STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Lmac_0646High-affinity nickel-transport protein; Belongs to the NiCoT transporter (TC 2.A.52) family. (232 aa)    
Predicted Functional Partners:
Lmac_0647
Cation transport ATPase.
       0.689
hypB
Hydrogenase nickel incorporation protein HypB.
     
 0.658
hypA
Hydrogenase nickel incorporation protein HypA; Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase.
     
 0.658
oxdC
Oxalate decarboxylase OxdC.
  
     0.626
hypE
Hydrogenase expression/formation protein HypE.
       0.611
hypD
Hydrogenase expression/formation protein HypD; Belongs to the HypD family.
       0.611
hypC
Hydrogenase expression/formation protein HypC.
       0.611
hypF
Hydrogenase maturation protein HypF; Involved in the maturation of [NiFe] hydrogenases. Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of [NiFe]-hydrogenases. HypF functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide.
       0.611
egl
Endoglucanase precursor; Belongs to the glycosyl hydrolase 5 (cellulase A) family.
  
     0.584
Lmac_0636
Sulfhydrogenase subunit delta.
       0.568
Your Current Organism:
Legionella maceachernii
NCBI taxonomy Id: 466
Other names: ATCC 35300, CCUG 31116, CIP 103846, DSM 16642, JCM 7566, L. maceachernii, NCTC 11982, Tatlockia maceachernii, strain Px-1-G-2-E2
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