Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
iraASmall-molecule methyltransferase IraA. (272 aa)    
Predicted Functional Partners:
pksJ
Polyketide synthase, type I.
    
 0.853
Lmac_0679
Hypothetical protein.
     
 0.831
Lmac_1506
Hypothetical protein.
  
     0.774
Lmac_2367
Coiled-coil protein.
  
     0.774
Lmac_1053
Hypothetical protein.
  
     0.773
Lmac_1255
Ankyrin repeats (3 copies).
  
     0.772
Lmac_1869
Hypothetical protein.
  
     0.771
Lmac_0701
Hypothetical protein.
  
     0.770
Lmac_1957
Type II/III secretion system protein.
  
     0.770
Lmac_2148
Polyketide synthase module.
    
 0.770
Your Current Organism:
Legionella maceachernii
NCBI taxonomy Id: 466
Other names: ATCC 35300, CCUG 31116, CIP 103846, DSM 16642, JCM 7566, L. maceachernii, NCTC 11982, Tatlockia maceachernii, strain Px-1-G-2-E2
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