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Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
hrp1Hypoxic response protein 1. (144 aa)    
Predicted Functional Partners:
guaA
GMP synthase; Catalyzes the synthesis of GMP from XMP.
    
 0.824
korA
2-oxoglutarate ferredoxin oxidoreductase subunit alpha.
 
  
  0.748
Lmac_0684
Hypothetical protein.
       0.704
Lmac_2436
PAS fold protein.
    
  0.584
Lmac_1043
2-oxoisovalerate dehydrogenase, E1 component, alpha and beta fusion.
     
  0.580
Lmac_0683
Glutamate synthetase.
       0.474
Lmac_0686
Hypothetical protein.
       0.470
Lmac_2459
2-oxoglutarate ferredoxin oxidoreductase beta subunit.
 
  
  0.468
Lmac_0053
Phospholipid binding protein.
       0.461
kdsA
2-dehydro-3-deoxyphosphooctonate aldolase; Belongs to the KdsA family.
  
 
 0.454
Your Current Organism:
Legionella maceachernii
NCBI taxonomy Id: 466
Other names: ATCC 35300, CCUG 31116, CIP 103846, DSM 16642, JCM 7566, L. maceachernii, NCTC 11982, Tatlockia maceachernii, strain Px-1-G-2-E2
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