STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
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Coexpression
Experiments
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[Homology]
Score
metNMethionine import ATP-binding protein MetN; Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system. (341 aa)    
Predicted Functional Partners:
Lmac_0708
29 kDa immunogenic protein.
 
 0.999
metI
Putative D-methionine transport system permease protein metI.
 
 0.999
Lmac_2715
ABC transporter permease.
 
     0.831
Lmac_0707
Coiled coil domain-containing protein.
       0.699
Lmac_2907
Sulfurylase ThiF.
     
 0.548
Lmac_1371
ABC transporter permease.
 
      0.533
cysK
Cystathionine beta synthase.
    
 0.493
Lmac_0711
Hypothetical protein.
       0.448
metK_1
S-adenosylmethionine synthetase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
   
  
 0.434
metK_2
S-adenosylmethionine synthetase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
   
  
 0.434
Your Current Organism:
Legionella maceachernii
NCBI taxonomy Id: 466
Other names: ATCC 35300, CCUG 31116, CIP 103846, DSM 16642, JCM 7566, L. maceachernii, NCTC 11982, Tatlockia maceachernii, strain Px-1-G-2-E2
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