STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Lmac_0816Threonine(-3-)dehydrogenase. (402 aa)    
Predicted Functional Partners:
frmC
S-formylglutathione hydrolase; Serine hydrolase involved in the detoxification of formaldehyde.
   
 
 0.773
korA
2-oxoglutarate ferredoxin oxidoreductase subunit alpha.
    
 0.710
Lmac_1043
2-oxoisovalerate dehydrogenase, E1 component, alpha and beta fusion.
  
 
 0.679
Lmac_0817
Eukaryotic DNA topoisomerase I, catalytic core.
 
     0.650
Lmac_2406
Acetyoacetyl CoA reductase.
  
  
  0.640
Lmac_0716
Putative hydrolase.
    
  0.604
frmA_2
Alcohol dehydrogenase; Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily.
   
 
  0.577
Lmac_1156
NADH dehydrogenase I subunit F; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Belongs to the complex I 51 kDa subunit family.
     
  0.549
pksJ
Polyketide synthase, type I.
    
 0.541
petC_2
Cytochrome b6-f complex iron-sulfur subunit.
 
  
 0.518
Your Current Organism:
Legionella maceachernii
NCBI taxonomy Id: 466
Other names: ATCC 35300, CCUG 31116, CIP 103846, DSM 16642, JCM 7566, L. maceachernii, NCTC 11982, Tatlockia maceachernii, strain Px-1-G-2-E2
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