| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| Lmac_1028 | Lmac_1029 | Lmac_1028 | Lmac_1029 | Coproporphyrinogen III oxidase. | Hypothetical protein. | 0.485 |
| Lmac_1028 | apt | Lmac_1028 | Lmac_1025 | Coproporphyrinogen III oxidase. | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | 0.773 |
| Lmac_1028 | fucA | Lmac_1028 | Lmac_1026 | Coproporphyrinogen III oxidase. | L-fuculose phosphate aldolase. | 0.773 |
| Lmac_1028 | metK_1 | Lmac_1028 | Lmac_1023 | Coproporphyrinogen III oxidase. | S-adenosylmethionine synthetase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme. | 0.490 |
| Lmac_1028 | mtnA | Lmac_1028 | Lmac_1024 | Coproporphyrinogen III oxidase. | Methylthioribose-1-phosphate isomerase; Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P). | 0.722 |
| Lmac_1028 | xapA_2 | Lmac_1028 | Lmac_1027 | Coproporphyrinogen III oxidase. | Xanthosine phosphorylase; Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates; Belongs to the PNP/MTAP phosphorylase family. MTAP subfamily. | 0.820 |
| Lmac_1029 | Lmac_1028 | Lmac_1029 | Lmac_1028 | Hypothetical protein. | Coproporphyrinogen III oxidase. | 0.485 |
| Lmac_1029 | apt | Lmac_1029 | Lmac_1025 | Hypothetical protein. | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | 0.485 |
| Lmac_1029 | fucA | Lmac_1029 | Lmac_1026 | Hypothetical protein. | L-fuculose phosphate aldolase. | 0.485 |
| Lmac_1029 | mtnA | Lmac_1029 | Lmac_1024 | Hypothetical protein. | Methylthioribose-1-phosphate isomerase; Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P). | 0.429 |
| Lmac_1029 | xapA_2 | Lmac_1029 | Lmac_1027 | Hypothetical protein. | Xanthosine phosphorylase; Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates; Belongs to the PNP/MTAP phosphorylase family. MTAP subfamily. | 0.485 |
| apt | Lmac_1028 | Lmac_1025 | Lmac_1028 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | Coproporphyrinogen III oxidase. | 0.773 |
| apt | Lmac_1029 | Lmac_1025 | Lmac_1029 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | Hypothetical protein. | 0.485 |
| apt | fucA | Lmac_1025 | Lmac_1026 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | L-fuculose phosphate aldolase. | 0.844 |
| apt | guaA | Lmac_1025 | Lmac_0556 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | GMP synthase; Catalyzes the synthesis of GMP from XMP. | 0.988 |
| apt | metK_1 | Lmac_1025 | Lmac_1023 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | S-adenosylmethionine synthetase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme. | 0.540 |
| apt | mtnA | Lmac_1025 | Lmac_1024 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | Methylthioribose-1-phosphate isomerase; Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P). | 0.782 |
| apt | pksJ | Lmac_1025 | Lmac_2149 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | Polyketide synthase, type I. | 0.507 |
| apt | ppt | Lmac_1025 | Lmac_1526 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | Hypoxanthine-guanine phosphoribosyltransferase. | 0.763 |
| apt | xapA_2 | Lmac_1025 | Lmac_1027 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | Xanthosine phosphorylase; Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates; Belongs to the PNP/MTAP phosphorylase family. MTAP subfamily. | 0.978 |