Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Lmac_1033ATP-dependent DNA helicase. (483 aa)    
Predicted Functional Partners:
Lmac_1032
Integrase.
       0.773
recG
ATP-dependent DNA helicase RecG; Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y- DNA); Belongs to the helicase family. RecG subfamily.
     
 0.648
Lmac_0856
Sensory box histidine kinase/response regulator.
   
  
 0.546
guaA
GMP synthase; Catalyzes the synthesis of GMP from XMP.
       0.539
Lmac_1031
Phage-related integrase; Belongs to the 'phage' integrase family.
       0.538
Lmac_3126
ATPase.
  
     0.521
Lmac_1850
ATP-dependent DNA helicase.
  
  
 
0.513
opuCC
Glycine betaine/carnitine/choline-binding protein OpuCC precursor.
  
  
 0.503
Lmac_2763
Protein of unknown function DUF1016.
 
     0.477
Lmac_0938
Filamentation induced by cAMP protein Fic.
 
  
  0.473
Your Current Organism:
Legionella maceachernii
NCBI taxonomy Id: 466
Other names: ATCC 35300, CCUG 31116, CIP 103846, DSM 16642, JCM 7566, L. maceachernii, NCTC 11982, Tatlockia maceachernii, strain Px-1-G-2-E2
Server load: low (16%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.